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Melatonin, the primary hormone of the pineal gland, is a powerful “”chronobiotic”” that helps maintain the body’s normal circadian rhythms.* In individuals who have difficulty sleeping or who have altered circadian rhythms because of jet lag or night shift work, melatonin supplementation supports the resynchronization of this cycle.* Supplementation can also benefit those whose difficulty sleeping is caused by the aging-related decrease in the body’s ability to synthesize melatonin from the amino acid tryptophan.* Research indicates melatonin exerts its sleep-supporting efficacy by decreasing the amount of time needed to fall asleep, by supporting the ability to stay asleep, and by supporting the depth of sleep.*