L-Glutamine is the most prevalent amino acid in the bloodstream. It is found in high concentration in the gastrointestinal tract, which is its greatest user.
Evidence suggests supplemental L-glutamine benefits gastrointestinal health, supports wound healing, maintains immune health and helps restore plasma glutamine levels depleted after periods of physical stress such as prolonged exhaustive exercise.
- Various stress factors – such as trauma, infection, malnutrition, chemotherapy, injury and high-level athletic training can adversely affect absorption in the small intestine, leading to food allergies.
- In numerous animal studies, the addition of L-glutamine improved absorption, as well as the gut’s immune function.
- Skeletal muscles contain the greatest intracellular concentration but that concentration can be adversely affected by various insults, including injury, infection, chronic stress, malnutrition and glucocorticoid use.
- Intense exercise lowers blood levels of glutamine, which can remain low if intense training is repeated without adequate recovery.
- Research indicates that supplementation can offset these conditions.