Hyaluronic acid or HA is a naturally occurring polymer found in every tissue of the body.
- It is particularly concentrated in the skin and in synovial fluid but decreases with aging.
- Many sources of HA consist of large molecular weight compounds that are too large to be absorbed in the intestines.
- It also appears to support the skin by promoting healthy turnover and renewal of keratinocytes.
- For joints, HA is especially supportive of healthy lubrication and shock absorption. Furthermore, in vitro studies indicate that HA modulates prostaglandin production, providing additional support for joint function.
- HyaMax® sodium hyaluronate provides a low molecular weight source of hyaluronic acid produced through fermentation.
- In a pharmacokinetic study conducted in animals, orally administered HyaMax® hyaluronic acid was incorporated into joints, connective tissue, and skin, with a particular affinity for cartilaginous joints.
- HA functions include attracting and retaining water in the extracellular matrix of tissues. For skin cells, this is essential for proper cell-to-cell communication, hydration, nutrient delivery, and waste and toxin elimination.